Welcome to HEDD

The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on the storage and integration of epigenetic drug datasets that were obtained from laboratory experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

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Drug Category

DNA methyltransferase inhibitor(DNMTi)
Histone acetyltransferases inhibitor(HATi)
  • C646 (CN:328968-36-1 Molecular Formula:C24H19N3O6)
  • Curcumin (CN:458-37-7 Molecular Formula:C21H20O6)
Histone deacetylase inhibitor(HDACi)
Histone demethylase inhibitor(HDMi)
  • Pargyline (CN:555-57-7 Molecular Formula:C11H13N)
  • clorgyline (CN:17780-72-2 Molecular Formula:C13H15Cl2NO)
  • bizine (CN:N.A. Molecular Formula:C18H24ClN3O)
  • GSK2879552 (CN:1401966-69-5 Molecular Formula:C23H28N2O2)
  • GSK-J4 (CN:1373423-53-0 Molecular Formula:C24H27N5O2)
  • KDM5-C70 (CN:N.A. Molecular Formula:C17H28N4O3)
  • JIB-04 (CN:199596-05-9 Molecular Formula:C17H13ClN4)
  • tranylcypromine (CN:155-09-9 Molecular Formula:C9H11N)
Histone methyltransferase inhibitor(HMTi)
  • EPZ-6438 (CN:1403254-99-8 Molecular Formula:C34H44N4O4)
  • GSK126 (CN:1346574-57-9 Molecular Formula:C31H38N6O2)
  • CPI360 (CN:N.A. Molecular Formula:C25H31N3O4)
  • 3-Deazaneplanocin A (CN:102052-95-9 Molecular Formula:C12H14N4O3)
  • GSK343 (CN:1346704-33-3 Molecular Formula:C31H39N7O2)
  • EI1 (CN:1418308-27-6 Molecular Formula:C23H26N4O2)
  • BIX-01294 (CN:935693-62-2 Molecular Formula:C28H38N6O2)
  • UNC0638 (CN:1255580-76-7 Molecular Formula:C30H47N5O2)
  • EPZ004777 (CN:1338466-77-5 Molecular Formula:C28H41N7O4)
  • UNC0224 (CN:1197196-48-7 Molecular Formula:C26H43N7O2)
Inhibitor of protein binding to acetylated histone (PAHi)
  • JQ1 (CN:1268524-70-4 Molecular Formula:C23H25ClN4O2S)
  • CPI203 (CN:1446144-04-2 Molecular Formula:C18H18ClN5OS)
  • RVX-208 (CN:1044870-39-4 Molecular Formula:C20H22N2O5)
  • I-BET151 (CN:1300031-49-5 Molecular Formula:C23H21N5O3)
  • I-BET762 (CN:1260907-17-2 Molecular Formula:C22H22ClN5O2)
  • i-BET-726 (CN:1300031-52-0 Molecular Formula:C25H23ClN2O3)
Inhibitor of protein binding to methylated histone(PMHi)
  • UNC669 (CN:1314241-44-5 Molecular Formula:C15H20BrN3O)
  • UNC1215 (CN:1415800-43-9 Molecular Formula:C32H43N5O2)

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The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on the storage and integration of epigenetic drug datasets that were obtained from laboratory experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

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©2016 Group of Computational Epigenomics and Bioinformatics, College of Life Science, Jilin Normal University, China

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