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The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on the storage and integration of epigenetic drug datasets that were obtained from laboratory experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

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G9a-like protein lysine methyltransferase inhibition by BIX-01294

PdbId:3FPD
Drug Name:BIX-01294
Target:Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (Homo sapiens)
Classification:TRANSFERASE
Method:X-RAY DIFFRACTION
Resolution(Å):2.4
Total Weight:62738.18 g/mol
PubmedID:19219047
Citation:Chang Y; Zhang X; Horton JR; Upadhyay AK; Spannhoff A; Liu J; Snyder JP; Bedford MT; Cheng X. Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294. (2009) Nat.Struct.Mol.Biol. 16: 312-317
Structure:
3D Structure:3D View
Structure Downlaod:3fpd.pdb(404.0KB)
Interaction:

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The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on integrating epigenetic drug studies based Omics data from high through experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

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©2016 Group of Computational Epigenomics and Bioinformatics, College of Life Science, Jilin Normal University, China

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