Welcome to HEDD

The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on the storage and integration of epigenetic drug datasets that were obtained from laboratory experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

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Complex list

PDBIdDrug NameTargetmethodPubmedId
4QD3 5-AzacytidinePeptidyl-tRNA hydrolase (Pseudomonas aeruginosa)X-RAY DIFFRACTION25101795
4AWM epigallocatechin-3-gallatePOLYMERASE (Influenza A virus)X-RAY DIFFRACTION22876177
3OOB epigallocatechin-3-gallatePeptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Homo sapiens)X-RAY DIFFRACTION21750208
3NG5 epigallocatechin-3-gallateTransthyretin (Homo sapiens)X-RAY DIFFRACTION20565072
2KDH epigallocatechin-3-gallateTroponin C, slow skeletal and cardiac muscles (Homo sapiens)NMR19542563
4PD7 ZebularineNupC family protein (Vibrio cholerae)X-RAY DIFFRACTION25082345
3LTW hydralazineArylamine N-acetyltransferase Nat (Mycobacterium marinum)X-RAY DIFFRACTION21203950
4LXZ Suberoylanilide hydroxamic acidHistone deacetylase 2 (Homo sapiens)X-RAY DIFFRACTION23897821
1ZZ1 Suberoylanilide hydroxamic acidHistone deacetylase-like amidohydrolase (Alcaligenaceae bacterium FB188)X-RAY DIFFRACTION16242151
4R7L Suberoylanilide hydroxamic acidLeukotriene A-4 hydrolase (Homo sapiens)X-RAY DIFFRACTION
4BZ6 Suberoylanilide hydroxamic acidHISTONE DEACETYLASE 8 (Schistosoma mansoni)X-RAY DIFFRACTION24086136
3C0Z Suberoylanilide hydroxamic acidHistone deacetylase 7a (Homo sapiens)X-RAY DIFFRACTION18285338
4QA0 Suberoylanilide hydroxamic acidHistone deacetylase 8 (Homo sapiens)X-RAY DIFFRACTION25075551
1T69 Suberoylanilide hydroxamic acidHistone deacetylase 8 (Homo sapiens)X-RAY DIFFRACTION15242608
1C3S Suberoylanilide hydroxamic acidHDLP (HISTONE DEACETYLASE-LIKE PROTEIN) (Aquifex aeolicus)X-RAY DIFFRACTION10490031
4QA2 Suberoylanilide hydroxamic acidHistone deacetylase 8(Homo sapiens)X-RAY DIFFRACTION25075551
5EF8 PanobinostatHdac6 protein (Danio rerio)X-RAY DIFFRACTION27454933
1T64 Trichostatin AHistone deacetylase 8 (Homo sapiens)X-RAY DIFFRACTION15242608
1C3R Trichostatin AHDLP (HISTONE DEACETYLASE-LIKE PROTEIN) (Aquifex aeolicus)X-RAY DIFFRACTION10490031
3C10 Trichostatin AHistone deacetylase 7a (Homo sapiens)X-RAY DIFFRACTION18285338
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The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on integrating epigenetic drug studies based Omics data from high through experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

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©2016 Group of Computational Epigenomics and Bioinformatics, College of Life Science, Jilin Normal University, China

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