Welcome to HEDD

The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on the storage and integration of epigenetic drug datasets that were obtained from laboratory experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

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Pivanex

Category:HDACi
Cas Number:122110-53-6
Molecular Formula:C10H18O4
Molecular Weight:202.24752 g/mol
Smiles:CCCC(=O)OCOC(=O)C(C)(C)C
Description:The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines.
synonyms:
Structure:
3D Conformer:3D View
Downlaod:Structure File Download (5.0KB)

Target list

IdDrug NameTargetPubmedIdCo-crystal Complex

Disease list

ConditionsDrug NameStatusNct NumberPhases
Malignant melanomaPivanexTerminatedNCT00087477Phase 1 2
Leukemia
lymphocytic
lymphoma
small lymphocytic
PivanexTerminatedNCT00083473Phase 2
Carcinoma
non-small-cell lung
Pivanex/docetaxelCompletedNCT00073385Phase 2

High-throughoutput Dataset

TitleDrug NameCategorySample typePMID

Complex list

PDBIdDrug NameTargetmethodPubmedId

About

pix

The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on integrating epigenetic drug studies based Omics data from high through experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

Copyright

©2016 Group of Computational Epigenomics and Bioinformatics, College of Life Science, Jilin Normal University, China

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