HEDD

Welcome to HEDD

The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on the storage and integration of epigenetic drug datasets that were obtained from laboratory experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

Pivanex

Category:	HDACi
Cas Number:	122110-53-6
Molecular Formula:	C₁₀H₁₈O₄
Molecular Weight:	202.24752 g/mol
Smiles:	CCCC(=O)OCOC(=O)C(C)(C)C
Description:	The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines.
synonyms:	Pivanex AN-9 122110-53-6 AN 9 AN 9 (ion exchanger) Butanoic acid, (2,2-dimethyl-1-oxopropoxy)methyl ester BRN 4861411 ((2,2-Dimethylpropanoyl)oxy)methyl butanoate 37380-45-3 Butanoic acid,(2,2-dimethyl-1-oxopropoxy)methyl ester C10H18O4 [(2,2-DIMETHYLPROPANOYL)OXY]METHYL BUTANOATE ACMC-20mpwb AC1L1TUK SCHEMBL356482 UNII-55VNK5440P CHEMBL100014 CTK4B2954 DTXSID40190818 GYKLFBYWXZYSOW-UHFFFAOYSA-N 55VNK5440P ZINC1545115 MFCD00209896 butanoyloxymethyl 2,2-dimethylpropanoate LS-46268 OR050285 OR264113 Butyric acid 2,2-dimethyl-propionyloxymethyl ester Butyric acid 2,2-dimethyl-propionyloxymethyl ester(AN9) BUTANOIC ACID (2,2-DIMETHYL-1-OXOPROPOXY)METHYL ESTER
Structure:
3D Conformer:	3D View
Downlaod:	Structure File Download (5.0KB)

Target list

Drug Name

Target

PubmedId

Co-crystal Complex

Disease list

Conditions	Drug Name	Status	Nct Number	Phases
Malignant melanoma	Pivanex	Terminated	NCT00087477	Phase 1 2
Leukemia lymphocytic lymphoma small lymphocytic	Pivanex	Terminated	NCT00083473	Phase 2
Carcinoma non-small-cell lung	Pivanex/docetaxel	Completed	NCT00073385	Phase 2

High-throughoutput Dataset

Title

Drug Name

Category

Sample type

PMID

Complex list

PDBId

Drug Name

Target

method

PubmedId

About

The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on integrating epigenetic drug studies based Omics data from high through experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

HEDD

Welcome to HEDD

Pivanex

Target list

Disease list

High-throughoutput Dataset

Complex list

About

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