Welcome to HEDD

The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on the storage and integration of epigenetic drug datasets that were obtained from laboratory experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

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Target list

IdDrug NameTargetPubmedIdCo-crystal Complex
1 5-Aza-2'-deoxycytidineexonuclease V (RecBCD complex), alpha chain (Escherichia coli str. K-12 substr. MG1655)
2 5-AzacytidineMultidrug and toxin extrusion protein 1 (Homo sapiens)23241029
3 epigallocatechin-3-gallateEnoyl-acyl-carrier protein reductase (Plasmodium falciparum)17263522
4 epigallocatechin-3-gallateCpG DNA methylase (Spiroplasma sp. (strain MQ-1))22854677
5 epigallocatechin-3-gallateEnoyl-acyl-carrier protein reductase (Plasmodium falciparum)17263522
6 epigallocatechin-3-gallateEnoyl-acyl-carrier protein reductase (Plasmodium falciparum)17263522
7 epigallocatechin-3-gallateDual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (RAT)12534346
8 epigallocatechin-3-gallateTyrosine-protein kinase Met (Homo sapiens (Human))19839593
9 epigallocatechin-3-gallateEnoyl-ACP Reductase (FabI) (Escherichia coli)17263522
10 epigallocatechin-3-gallateEnoyl-acyl-carrier protein reductase (Plasmodium falciparum)17263522
11 epigallocatechin-3-gallateSqualene monooxygenase (Rattus norvegicus)11520216
12 epigallocatechin-3-gallateMatrix metalloproteinase 7 (Homo sapiens (Human))19524436
13 epigallocatechin-3-gallate72 kDa type IV collagenase (homo sapiens (human))19524436
14 epigallocatechin-3-gallateMatrix metalloproteinase 14 (Homo sapiens)19524436
15 epigallocatechin-3-gallateTyrosine-protein kinase Met (Homo sapiens (Human))19839593
16 epigallocatechin-3-gallateLeukocyte elastase (Homo sapiens (Human))20004577
17 epigallocatechin-3-gallatePOsterior Segregation family member (pos-1) (Caenorhabditis elegans)
18 epigallocatechin-3-gallateRecName: Full=Zinc finger protein mex-5 (Caenorhabditis elegans)
19 epigallocatechin-3-gallateMAP kinase p38 (Homo sapiens (human))21080642
20 epigallocatechin-3-gallateAlpha-(1,3)-fucosyltransferase VII (HUMAN)15081893
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The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on integrating epigenetic drug studies based Omics data from high through experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.

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©2016 Group of Computational Epigenomics and Bioinformatics, College of Life Science, Jilin Normal University, China

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